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Volume-2 (2003);
Issue 3 (July-September)
Published on Oct 7, 2003
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2003;3-1 -
Original Article |
| Idu FK,
Odjimogho SE.
Susceptibility of conjunctival bacterial
pathogens to fluoroquinolones: A comparative study of ciprofloxacin, norfloxacin and
ofloxacin |
Abstract:
In order to determine
the most common bacteria implicated in conjunctivitis, and the effectiveness of the
antibiotic Fluoroquinolone for its treatment, a total of 50 subjects (100 ) eyes, between
the ages of 1-30 years with mean age of 16.94 ± 8.06 years with infected eyes, were
examined at the Lagos State University Teaching Hospital, Nigeria (LASUTH). Conjunctival
swabs were collected and cultured in the laboratory to isolate the pathogens responsible
for the infection. Sensitivity and antibiotic suscepticibility tests were carried out with
discs impregnated with 0.3% concentration of ophthalmic topical solutions of chibroxin
(Norfloxacin), ciloxan (Ciprofloxacin), and ocuflox (Ofloxacin), to ascertain the
most sensitive of the three drugs. The results showed that the implicated bacteria in
order of decreasing frequency were Staphylococcus aureus (34%), followed by
Streptococcus pneumoniae (22%), Pseudomonas aeruginosa (14%), Klebsiella
pneumoniae (12%), Hemophilus influenzae (9%), Escherichia coli (9%). All
the isolated organisms were highly sensitive to the three drugs. However, a one way
analysis of variance (ANOVA) showed a significant difference in the sensitivity of the
three drugs (p< 0.05). ANOVA Post Hoc located Ciprofloxacin as the source of the
significance. In conclusion therefore, Ciprofloxacin is the most sensitive of the three
drugs and, hence should be the first choice of the fluoroquinolones for the treatment of
bacterial conjunctivitis.
Key words: Conjunctivitis,
fluoroquinolones |
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2003;3-2
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Case Report |
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Sathish Bhandary. Innovative Surgical Technique in the
Management of Vallecular Cyst |
Abstract:
A retention cyst arising from the
vallecula in a 30 year old man was surgically excised using an Eve’s Tonsillar snare
and there was no recurrence after 6 months follow-up.
Key words: Vallecular cyst, snaring |
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This Article |
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